| 张沪伟,王鹏,张盾.一种硫离子响应杀菌材料的制备及应用研究[J].装备环境工程,2018,15(10):67-71. ZHANG Hu-wei,WANG Peng,ZHANG Dun.Preparation and Research of a Sulfide Ion Responsive Antiseptic Material[J].Equipment Environmental Engineering,2018,15(10):67-71. |
| 一种硫离子响应杀菌材料的制备及应用研究 |
| Preparation and Research of a Sulfide Ion Responsive Antiseptic Material |
| 投稿时间：2018-07-13 修订日期：2018-10-25 |
| DOI：10.7643/ issn.1672-9242.2018.10.011 |
| 中文关键词: 埃洛石纳米管 硫离子响应释放 络合物膜层 甲硝唑 |
| 英文关键词:halloysite nanotubes sulfide ion responsive release complex film metronidazole |
| 基金项目: |
|
|
| Author | Institution |
| ZHANG Hu-wei | 1. Key Laboratory of Marine Environmental Corrosion and Biofouling, Institute of Oceanology, Chinese Academy of Science, Qingdao 266071, China;2. University of Chinese Academy of Sciences, Beijing 100049, China;3. Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao 266071, China |
| WANG Peng | 1. Key Laboratory of Marine Environmental Corrosion and Biofouling, Institute of Oceanology, Chinese Academy of Science, Qingdao 266071, China;3. Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao 266071, China |
| ZHANG Dun | 1. Key Laboratory of Marine Environmental Corrosion and Biofouling, Institute of Oceanology, Chinese Academy of Science, Qingdao 266071, China;3. Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao 266071, China |
|
| 摘要点击次数: |
| 全文下载次数: |
| 中文摘要: |
| 目的 制备硫离子响应杀菌材料，研究它在不同浓度铜离子条件下的封装效果，以及在不同浓度硫离子条件下的释放行为。方法 选择埃洛石纳米管为载体并用透射电镜进行表征、采用真空负载的方式，将甲硝唑和苯骈三氮唑（BTA）分步填充到埃洛石纳米管内部，使用紫外分光光度法测试不同浓度铜离子对纳米管中甲硝唑的封堵效果，以及材料在不同浓度硫离子条件下的释放情况。结果 实验中通过调整铜离子浓度发现，铜离子浓度越大对甲硝唑的封堵效果越好，当铜离子浓度达到160 mmol/L时，对甲硝唑的封堵效果最好。杀菌材料在外界硫离子达到0.1 mmol/L后，甲硝唑的释放浓度迅速提高，进一步提高硫离子浓度，释放情况改变不明显。结论 铜离子浓度达到160 mmol/L时，材料的封装效果是最好的。材料能够对硫离子实现响应释放，且对应的临界浓度为0.1 mmol/L。 |
| 英文摘要: |
| Objective To prepare sulfide ion responsive antiseptic materials and study the effect of its packaging in different concentration of copper ion and the release behavior in different concentration of sulfide ion. Method Halloysite nanotubes were chosen as the carrier and characterized by transmission electron microscopy. Under vacuum conditions, metronidazole and ben-zotriazole (BTA) were loaded into the internal of the halloysite nanotubes in order. The sealing effect of metronidazole in the nanotubes under different concentration of copper ion and the release circumstance of metronidazole under different concentration of sulfide ion was tested with ultraviolet spectrophotometry. Results The higher copper ion concentration was, the better sealing effect of metronidazole was. When the copper ion concentration was 160 mmol/L, the sealing effect of metronidazole reached the best; the release concentration of metronidazole increased rapidly after the external concentration of sulfide ion reached 0.1 mmol/L and the release concentration of metronidazole didn’t change a lot when the concentration of sulfide ion was further increased. Conclusion The best encapsulation conditions of metronidazole in the nanotube were ensured by adjusting the concentration of copper ion to 160 mmol/L. The antiseptic materials can respond to the sulfide ions and the corresponding critical concentration is 0.1 mmol/L. |
| 查看全文 查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
